软珊瑚Sarcophyton sp.中一个新西松烷型二萜的结构解析

摘要

对南海软珊瑚Sarcophyton sp.中的西松烷二萜类成份进行研究,从发现具有新颖结构的次生代谢产物.采用多种色谱手段进行分离纯化,通过理化性质和光谱分析确定化合物结构.分离得到1个新的西松烷二萜类化合物,命名为Sarcophyolide A(1),和一个已知西松烷二萜类化合物7α,8β-dihydroxydeepoxysarcophine(2).利用现代波谱确定新化合物的结构.%To investigate the eembranoid diterpenes from the soft coral Sarcophyton sp. collected in the South China Sea. Re-peatedly column chromatography was performed for the isolation and purification. The structures were elucidated on the basis of extensive spectral data (IR, MS, ID- and 2D-NMR) analysis by comparing with literature data. A new eembranoid diterpene namely sareophyolide A (1), together with 7a, 8β-dihydroxydeepoxysareophine (2) were isolated from this species. The cembra-noid diterpenes with γ-lactone could be chemotaxonomic markers ofSarcophyton sp.