107例病毒性脑炎患者近期预后相关因素分析

摘要

目的 分析病毒性脑炎患者近期预后相关因素.方法 回顾性分析107例病毒性脑炎患者病程早期的临床资料,比较预后良好及预后不良患者(包括后遗症及死亡患者)的临床特征,探讨影响患者早期预后的因素.结果 在单因素分析中,年龄、早期意识障碍、EEG异常、颅脑MR异常、CK升高等因素在预后良好及预后不良组之间差异具有统计学意义(P＜0.05);经多变量Logistic回归分析,筛选出年龄、早期意识障碍、颅脑磁共振异常是病毒性脑炎患者预后的独立危险因素.结论 病毒性脑炎患者年龄大、存在早期意识障碍、颅脑磁共振异常多提示预后不良.%Objective To analyze the factors associated with the prognosis in patients with viral encephalitis. Methods Retrospective analysis of the clinical data related to 107 cases of viral encephalitis patients in early stage, by comparing the clinical features between the good and poor prognosis patients (including patients with sequelae and death). The SPSS 19.0 was used to analyze the clinical data and discussed the prognostic factors. Results In the univariate analysis,age,early conscious disturbance,abnormal EEC,abnormal brain MRI,elevated crean'ne kinase and other factors were significantly different between the good and poor prognosis patients. The multivariable logistic regression analysis showed age,early conscious disturbance and abnormal brain MRI (P < 0.05) were the independent risk factors for the prognosis of viral encephalitis patients. Conclusion The older patients, early conscious disturbance and abnormal brain MRI with viral encephalitis had poor prognosis.