3D-SPACE双反转恢复序列在多发性硬化空间多发性的MR诊断中的价值

摘要

目的:探讨3D-SPACE(Sampling perfection with application-optimized contrasts by using different flip angle evo-lutions)双反转恢复(Double inversion recovery,DIR)序列在多发性硬化(Multiple sclerosis,MS)空间多发性的MR诊断中的应用价值.方法:对18例行3D-SPACE DIR序列和液体衰减反转恢复(FLAIR)序列扫描的MS患者的影像资料进行回顾性分析,查看它们显示病灶的空间分布情况.结果:18例MS患者,在小脑幕下,3D-SPACE DIR序列显示了10例患者存在分布于脑干或小脑的幕下病灶,而FLAIR序列未明显显示幕下病灶;在小脑幕上,FLAIR序列显示病灶的空间分布与3D-SPACE DIR序列相比,差别不明显,但清晰度不如3D-SPACE DIR序列.结论:3D-SPACE DIR序列在探查MS病灶的空间分布及数量方面明显优于FLAIR序列,尤其对于小脑幕下的病灶,其可以作为常规MR扫描序列的有利补充.%Objective: To investigate the diagnostic value of 3D sampling perfection with application optimized contrasts by using different flip angle evolutions (SPACE) double inversion recovery (DIR) sequence for dissemination in space in multiple sclerosis(MS). Methods: 3D-SPACE DIR and fluid-attenuated inversion recovery(FLAIR) sequence data of 18 patients with MS were analyzed retrospectively, and the space distribution of the lesions was examined. Results: In 18 cases of MS, in subten-torial, 3D-SPACE DIR sequence displayed 10 patients with lesions located in the brainstem or cerebellum, while the FLAIR sequence had no obvious display subtentorial lesions; FLAIR sequence displaying distribution of lesions was not significantly different from 3D-SPACE DIR sequence in the supratentorial region, but the definition was not as good as the 3D-SPACE DIR sequence. Conclusion: 3D-SPACE DIR sequence is superior to FLAIR sequence in detecting the space distribution and quantity of MS lesions, especially for the infratentorial lesions, which can be used as a favorable supplement to conventional MR scanning.