Objective To investigate the effect of treatment of late-stage spreading tumor (LST) after endoscopic submucosal dissection (ESD) on the prevention of complications and wound healing.Methods 94 patients with large-bowel lateralized tumors of 2 mm to 3.5 mm in diameter were subjected to ESD treatment. The patients were fasted, rested in bed, observed the changes of the disease and observed whether abdominal pain or hematochezia occurred. Among them, 52 cases were treated by oral and enema with Chinese medicine as experimental group, taking 42 cases as control group.Results In the first week, the cure rate in the test group was 28.85％ and the total healing rate was 61.54％, which was higher than that in the control group (7.14％) and 35.71％ (P<0.05). The cure rate in the trial group was 64.46％, which was higher than that in the control group (42.86％,P<0.05). In the third week, the healing rate of the experimental group was 86.54％, the total healing rate was 100％, which was significantly higher than the control group (57.14％, 90.48％)(P<0.05).Conclusion this traditional Chinese medicine therapy can promote the healing of ulcer after ESD, and it can be used as routine treatment for large intestine after ESD.%目的 探讨大肠侧向发育型肿瘤(LST)于内镜黏膜下剥离术(ESD)后使用中药处理,对防止并发症及创面愈合的效果.方法对94例基底部直径2～3.5 mm的LST行ESD治疗,于术后禁食,卧床休息,密切观察病情变化,注意是否发生腹痛、便血等不良反应.其中52例作为试验组给予中药口服及灌肠治疗,42例作为对照组.评价2组疗效标准.结果第1周,试验组痊愈率28.85％,总愈合率61.54％,高于对照组的7.14％和35.71％(P<0.05);第2周,试验组痊愈率64.46％高于对照组的42.86％(P<0.05);第3周,试验组痊愈率86.54％,总愈合率100％,明显高于对照组的57.14％和90.48％(P<0.05).结论该中药疗法对ESD术后溃疡愈合具有一定促进作用,可作为大肠ESD术后常规治疗手段.
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