主动脉内球囊反搏在心血管危重症患者中的临床应用

摘要

Objective: To estimate the therapeutic effect and safety of intra-aortic balloon pumps (IABP) in patients with serious cardiovascular diseases.Methods: We retrospectively analyzed the clinical data of 68 patients with serious cardiovascular diseases, who were enrolled in Hunan Provincial Peoples Hospital between 2009 and 2011. All patients received IABP support. The systolic blood pressure, diastolic blood pressure,heart rate, N-terminal precursor of brain natriuretic peptide (NT-proBNP), and renal function of all patients were determined before and after the IABP. Cardiac events and mortality were observed after IABP support.Results: The disease in 51 patients improved after IABP support. The systolic blood pressure, diastolic blood pressure,heart rate, and NT-proBNP were significantly lower than those before the IABP. Thirty-seven patients with acute myocardial infarction successfully completed percutaneous coronary intervention surgery after the IABP support. Five patients had IABP-related complications, but no serious complication occurred. Conclusion: IABP is an effective and safe procedure for critical cardiovascular patients. IABP should be applied early for the patients with appropriate indications.%目的:评价心血管危重症患者应用主动脉内球囊反搏(intra-aortic balloon pump,IABP)的疗效和安全性.方法:回顾性分析2009-2011年湖南省人民医院68例心血管危重症患者行IABP辅助治疗的临床资料.对所有入组患者分别于床旁或导管室行IABP辅助治疗,比较使用IABP前后患者的收缩压、舒张压、心率、N末端前体脑利钠肽以及肾功能.同时观察患者院内心血管事件及转归.结果:68例患者经IABP辅助治疗后有51例病情好转.37例患者在IABP置入后顺利完成冠状动脉介入治疗.IABP置入后患者收缩压、舒张压、心率及N末端前体脑利钠肽值下降.仅5例患者发生IABP相关并发症,无一例发生严重并发症.结论:IABP是抢救危重心血管病患者安全、有效的措施,对有适应证的患者应及早使用.