Objective: The aim of this study to assess the correlations of left atrial strain rate by using two-dimensional speckle tracking echocardiography (STE) with left ventricle diastolic function on the population in community. Methods:708 subjects with normal LVEF in community were studied. All subjects were classified three different LV diastolic function groups by using Doppler images of mitral inflow maneuver, Doppler images of pulmonary venous flow,and tissure Doppler images of mitral annular motion; group A(the normal one) 、 group B(the mild damaged one) , group C(the moderate/severe damaged one). We identified peak positive SRs at the beginning of LV systole, peak negative SRe at the beginning of LV diastole and SRa at the end of LV diastole by two-dimensional STE. Results:①SRs in group B and C were lower than group A, (1. 07 ±0. 35) s-1(0. 90 ±0. 24)s-1 and (1. 12 ±0. 28)s-1 (P<0. 01) ,also SRe in group B and C were lower than group A, ( -0.79 ±0.35) s-1、( -0. 65 ±0. 29)s-1 and ( - 1. 02 ±0. 33)s-1 (P <0. 01) ;SRa in group B is higher than group A[ ( - 1. 60 ±0. 58) s-1 and ( - 1. 48 ±0. 47) s-1 ,P <0. 05] ,and than group C[ ( - 1. 60 ± 0.58) s-1 and( -1.24±0.48) s-1 ,P<0. 01 ]. Furthermore SRa in group C is significantly lower than group A[ ( - 1. 24 ±0. 48) s-1 and ( - 1. 48 ±0. 47) s-1 ,P <0. 01 ]. ②SRs、SRe were negative correlated with LV diastolic function groups (r = -0. 178 and -0. 366,P <0. 01). Conclusion; LV diastolic function were eval-uated indirectly with LA strain rate by 2D speckle tracking technology.%目的:应用二维斑点追踪技术评价社区人群左心房应变率,及其与左心室舒张功能分级的相关性.方法:研究对象为左心室射血分数正常的社区人群,共708例脱机处理,根据多普勒二尖瓣口血流、二尖瓣环组织、肺静脉血流对左心室舒张功能进行分组:A组(左心室舒张功能正常组)、B组(左心室舒张功能轻度受损组)、C组(左心室舒张功能中/重度受损组).采用二维斑点追踪技术(STE),测量收缩期左心房应变率峰值SRs,舒张早期左心房应变率峰值SRe和舒张晚期左心房应变率峰值SRa.结果:①B组、C组SRs较A组降低,分别为(1.07 ±0.35) s-1、(0.90±0.24) s-1和(1.12±0.28)s-1(P＜0.01),B组、C组SRe较A组亦明显降低,分别为(-0.79 ±0.35)s-1、(-0.65 ±0.29)s1和(-1.02±0.33)s-1 (P＜0.01)；SRa在B组高于A组[分别为(-1.60±0.58) s-1和(-1.48±0.47)s-1,P＜0.05],亦高于C组[分别为(-1.60±0.58)s-1和(-1.24±0.48)s-1,P＜0.01],且C组显著小于A组[分别为(-1.24±0.48)s-1和(-1.48±0.47)s-1,P＜0.01].②SRs、SRe与左心室舒张功能分级均呈负相关(r分别为-0.178和-0.366,P＜0.01).结论:二维斑点追踪技术测量左心房应变率,可间接反映左心室舒张功能.
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