支气管扩张患者痰培养检出菌及药敏结果分析

摘要

Objective: To investigate the distribution and drug sensitivity of the bacteria obtained from sputum of patients with bronchiectasis and to provide scientific evidence for clinical therapy. Methods o Sputum bacterial culture and drug sensitive test of 212 bronchiectasis patients admitted into Beijing Anzhen Hospital from July 2007 to July 2011 were analyzed retrospectively. Results: There were 95 positive cases (44.81 % ) from sputum culture among 212 patients. Ninty-six bacteria strains were isolated in total, which included 29 cases of Pseudomonas aenigmosa (30. 2% ) , 7 cases of Klebsiella pneumoniae (7. 29% ), 4 cases of Pseudo-monas maltophilia (4. 17% ), 3 cases of Escherichia coli (3.13% ), 2 cases of Enterobacter aerogenes (2.08%), 2 cases of Enterobacter cloacae (2.08%),2 cases of Citrobacter freundii (2. 08%) ,2 cases of Pseudomonas fluorescens (2.08% ) , 1 case of Burkholderia cepacia (1.04% ) , 10 cases of Calcium Acetate-Bowman Acinetobacter (10.42% ), 2 cases of Acinetobacler calcoaceticus (2.08% ), 4 cases of Acinetobacter baumannii (4. 17% ), 1 case of Acinetobacter lwoffii ( 1. 04% ) , 12 cases of Staphylococcus aureus (12. 50% ), 4 cases of Staphylococcus epidermidis (4. 17% ), 2 cases of Staphylococcus haemolyticus (2. 08% ), 1 case of Simulation aureus (1. 04% ) , 1 case of Slow moving Streptococcus (1. 04% ). 1 case of En-terocoeeus casselifavus (1. 04% ), 2 cases of Enterococcus faecalis (2. 08% ) and 4 cases of Candida albi-cans (4. 17%). Conclusion:The top three bacteria are Pseudomonas aeruginosa and Staphylococcus aureus and Calcium Acetate-Bowman Acinetobacter in patients with bronchiectasis. Clinicians should pay more attention to fungal infection and rationally use antibiotics for the patients.%[目的]:分析支气管扩张患者痰培养检出菌的分布及对抗菌药物的敏感性,为临床提供药物治疗依据.[方法]:对2007年7月至2011年7月,对北京安贞医院住院的212例支气管扩张患者,痰致病菌培养及药物敏感结果进行回顾性分析.[结果]:本组212例患者病原菌检出阳性95例(44.81％),共分离出细菌96株,铜绿假单胞菌29株(30.2％),肺炎克雷伯杆菌7株(7.29％),嗜麦芽假单胞菌4株(4.17％),大肠埃希氏菌3株(3.13％),产气肠杆菌2株(2.08％),阴沟肠杆菌2株(2.08％),弗氏柠檬酸杆菌2株(2.08％),荧光假单胞菌2株(2.08％),洋葱伯克霍尔德式菌1株(1.04％),醋酸钙-鲍曼氏不动杆菌10株(10.42％),醋酸钙不动杆菌2株(2.08％),鲍曼氏不动杆菌4株(4.17％),鲁氏不动杆菌1株(1.04％),金黄色葡萄球菌12株(12.50％),表皮葡萄球菌4株(4.17％),溶血葡萄球菌2株(2.08％),模拟葡萄球菌1株(4.17％),缓动链球菌1株(1.04％),铅黄肠球菌1株(1.04％),粪肠球菌2株(2.08％),白色假丝酵母4株(4.17％).[结论]:支气管扩张患者病原菌占前3位的分别是铜绿假单胞菌、金黄色葡萄球菌、醋酸钙-鲍曼氏不动杆菌.真菌感染应值得关注.提示支气管扩张患者应合理选用抗生素药物.