青年缺血性卒中患者危险因素分析

摘要

Objective To evaluate the etiology and risk factors of young ischemic stroke patients. Methods From January 2002 to June 2007, 102 patients with acute ischemic stroke were enrolled in this study. Ischemic stroke was classified into five subtypes following modified Trial of Org 10172 in Acute Stroke Treatment ( TOAST ) criteria and corresponding risk factors were analyzed . Results The percentage of each modified TOAST subtypeswas as following: atherothrombosis 44. 12% , small-artery occlusion lacunars 30. 39% , cardioembolism 6. 86% , stroke of other demonstrated etiology 5. 88% , stroke of other undemonstrated etiology 12. 75% . The constituent ratios of the risk factors were hypertension 69. 61% , smoking 58. 82% , hyperlipemia 43. 14% , drinking 39. 22% , family history of stroke 24. 51% and diabetes 20. 59%. Conclusions Atherothrombosis and small-artery disease have comparatively large proportion among young ischemic stroke patients. Hypertension, smoking, hyperlipemia, drinking are common risk factors of young ischemic stroke patients.%目的 探讨国人青年缺血性卒中患者的病因学及危险因素.方法 以2002年1月至2007年6月期间入住河北医科大学第三医院神经内科的青年缺血性脑卒中患者作为研究对象,依据改良的TOAST病因分型法作为分型标准确定患者的卒中亚型,并分别计算各缺血性卒中危险因素的构成比.结果本组患者改良的TOAST亚型构成比例为动脉粥样硬化脑梗死型44.12%,小动脉病变型30.39%,心源性栓塞型6.86%,其它病因明确型5.88%,不明病因型12.75%;青年缺血性卒中患者危险因素构成比由高到低分别为高血压病69.61%、吸烟58.82%、高脂血症43.14%、饮酒39.22%、脑血管病家族史24.51%、糖尿病20.59%.结论 国人青年缺血性卒中患者中动脉粥样硬化脑梗死型和小动脉病变型仍占较大比例;高血压病、吸烟、高脂血症及饮酒是青年型缺血性卒中的主要危险因素.