Objective To study the effect of hydrocortisone for patients with refractoriness hyponatremia after Cerebral Trauma. Methods To review the data of 53 patients with refractoriness hyponatremia after Cerebral Trauma in the Second Hospital of Hehei Medical University from July, 2008 to July, 2010. Evaluating treatment methods according to the patient's treatment effect. Results In the 53 cases ,37 cases' blood natrium all revive normal by in time fluid replacement supply natrium to treat, the rest 26 cases'UNa and urinary were increased, and needed further supply natrium treatment. Hydrocortisone made UNa and urinary significantly reduced( P ＜ 0. 05 ),and could make blood natrium all revive normal. Conclusion Hydrocortisone can correct hyponatremia utility in time and has important sense on improving patient's prognosis. It has good the effect of hydrocortisone for patients with refractoriness hyponatremia after cerebral trauma.%目的 探讨氢化可的松对脑外伤后顽固性低钠血症的治疗效果.方法 对2008年7月-2010年7月我院收治的53例脑外伤后低钠血症患者进行回顾性分析,根据患者的治疗效果对治疗方法 进行评估.结果 在53例患者中,37例通过单纯的补钠使血钠水平恢复.其余的16例表现为尿钠、尿量增多和需要进一步保钠治疗.氢化可的松使尿钠排出显著减少、尿量减少(P＜0.05),并能使血钠恢复到正常范围.结论 氢化可的松对脑外伤后的顽固性低钠血症治疗效果理想,能够在短时间内及时纠正血钠,对提高患者的预后有重要的临床意义.
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