葛根芩连五炭汤联合柳氮磺吡啶治疗活动期溃疡性结肠炎临床研究

摘要

Objective To investigate clinical effect of Gegen Qinlian five carbon decoction combined with sulfasalazine in treatment of ulcerative colitis.Methods Eighty patients with ulcerative colitis were randomly divided into control group and treatment group with 40 cases in each group.Both were given oral salazosulfa pyridine and the treatment group was given additional medication of Gegen Qinlian decoction orally for a total of 4 courses.Curative effect was compared.Results In the treatment group,subsiding times of abdominal pain,hematochezia,diarrhea,tenesmus were shorter than that of the control group ( P <0.01).Total efficiency rate of treatment group was 95.00%,higher than that of the control group (77.50%, P <0.05).Conclusion Gegen Qinlian five carbon de-coction combined with sulfasalazine in treatment of active ulcerative colitis is effective and can reduce time for symptom improvement and is clinically worthy.%目的：探讨葛根芩连五炭汤联合柳氮磺吡啶治疗活动期溃疡性结肠炎的临床效果。方法将80例活动期溃疡性结肠炎患者随机分为两组，各40例。两组患者均给予口服柳氮磺砒啶治疗，观察组在上述治疗基础上加用葛根芩连五炭汤口服，共治疗4个疗程。对比两组临床治疗效果。结果观察组患者腹痛、便血和里急后重消失时间均短于对照组（ P ＜0．01）；观察组治疗总有效率为95．00％，高于对照组的77．50％（ P ＜0．05）。结论葛根芩连五炭汤联合柳氮磺吡啶治疗活动期溃疡性结肠炎效果显著，有助于缩短症状改善时间，值得临床推广应用。