2型糖尿病患者血脂水平与骨密度的相关性

摘要

目的:分析2型糖尿病(T2DM)患者血脂水平与骨密度的相关性,探讨T2DM患者血脂干预对骨密度的可能影响.方法:选择T2DM患者231例,按性别分为2组,每组再根据血脂水平分为不同的血脂亚组.对不同性别患者的血脂指标和骨密度进行相关性分析.结果:男性T2DM患者三酰甘油与腰椎、右髋和股骨颈骨密度均呈正相关关系(P<0.01),绝经后女性高密度脂蛋白与腰椎、右髋和股骨颈骨密度均呈负相关关系(P<0.05~P<0.01).结论:T2DM患者男性较高三酰甘油水平、绝经后女性较低高密度脂蛋白水平可能对骨密度具有正面作用.%Objective: To investigate the correlation of bone density and blood lipids levels in diabetic patients and know the effects of blood lipids on bone density. Methods: Two hundred and thirty-one cases with type 2 diabetes were divided into two groups, which were subdivided into different blood lipid group according to the blood lipids levels. The correlation of bone density and blood lipids levels of different sexes were analysed. Results: The data of simple linear correlation demonstrated that the triglyceride levels in males were a positive correlativity with bone density(P<0.01) and high density lipid in females were negative correlativity with bone density(P<0.05 -P < 0.01). Conclusions: High triglyceride in males and low high density lipid in postmenopausal females may have some protective effect on bone density.