七氟烷吸入麻醉对肝硬化行肝部分切除术病人镇痛效果及肝功能水平的影响

摘要

目的:探讨七氟烷吸入麻醉对肝硬化行肝部分切除术病人镇痛效果及血清丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)水平的影响.方法:选取肝硬化病人80例,依据随机数字表法分为七氟烷吸入麻醉组(七氟烷组,n=40)和丙泊酚泵注麻醉组(丙泊酚组,n=40),对2组病人的血清ALT、AST水平及镇痛效果进行统计分析.结果:七氟烷组病人的自主呼吸恢复时间、呼之睁眼时间及拔管时间均明显短于丙泊酚组(P0.05),疼痛视觉模拟评分明显降低(P0.05),and the VAS score in two groups significantly decreased after operation(P <0.01),and the VAS score in sevoflurane group was lower than that in propofol group after operation(P<0.01).Conclusions:The sevoflurane anesthesia do not increase the serum levels of ALT and AST and injure the liver in cirrhosis patients treated with partial hepatectomy,and the analgesic effect of which is good.