同步检测眼性和颈性前庭诱发肌源性电位的可行性研究

摘要

Objective To study the feasibility of simultaneously recording ocular vestibular-evoked myogenic potential (oVEMP) and cervical vestibular-evoked myogenic potential (cVEMP) by combined oVEMP and cVEMP tests.Methods Twenty healthy volunteers and twenty-three patients with Meniere's disease were admitted and underwent combined oVEMP and cVEMP tests in a random order,and individual oVEMP and cVEMP tests on another day.The results of combined and individual oVEMP and cVEMP tests were compared.Results For twenty healthy volunteers in oVEMP and cVEMP tests,the 100％ response rate were observed in the both combined and individual test modes.The differences in amplitudes and latencies and interaural amplitude difference were insignifi-cant.For twenty-three patients with Meniere's disease,the results of oVEMP/cVEMP for the affected and unaffected ears failed to sow any significant differneces,regardless of the individual or combined mode.Conclusion The simultaneous recording of oVEMP and cVEMP by the combined mode has similar results to that obtained by individual mode for both healthy or unilateral vestibular hypofunction.Simultaneous oVEMP and cVEMP tests may be a convenient screening test and deserves further clinical applications.%目的 探讨同步检测眼性前庭诱发肌源性电位(ocular vestibular-evoked myogenic potential,oVEMP)和颈性前庭诱发肌源性电位(cervical vestibular-evoked myogenic potential,cVEMP)的可行性.方法 对20例正常人及23例梅尼埃病患者分别进行oVEMP和cVEMP同步检测和单独检测,两种检测方式所用仪器和坐姿相同,检测参数设置相同,分别比较两种检测方式下两组对象oVEMP和cVEMP的振幅、潜伏期、波间期及双侧耳不对称比.结果 正常人左、右耳的oVEMP及cVEMP的引出率、振幅、潜伏期、波间期与不对称比在两种形式同步检测与各方式单独检测之间无显著差异;两种方式同步检测时梅尼埃病患者的患耳及对侧耳的oVEMP及cVEMP引出率、振幅、潜伏期、波间期及不对称比与各方式单独检测的结果也无显著差异.结论 对正常人和梅尼埃病患者,oVEMP和cVEMP检测可同步进行,但检测参数应与单独检测时设置一致.