东北刺人参茎耐缺氧及抗运动性疲劳作用研究

摘要

[目的]观察东北刺人参茎对小鼠的耐缺氧、抗疲劳作用,为开发利用其药用资源提供依据.[方法]用不同剂量东北刺人参茎给正常小鼠连续灌胃14 d,测定其负重游泳时间、耐缺氧时间;检测运动小鼠血乳酸含量.[结果]东北刺人参茎5.2、2.6、1.3 g/kg剂量组能延长小鼠的耐缺氧时间和负重游泳时间,且能降低小鼠血乳酸含量.[结论]东北刺人参茎有提高耐缺氧、抗疲劳能力的作用.%[ Objective ] To observe the anti-fatigue and anti-hypoxia effects of the stems of Oplopanax elatus Nakai in mice. [ Method ］ Given with different doses of O. elatus water suspension for 14 days, the swimming endurance, anti-hypoxia duration, and content of blood lactic acidof mice were determined. [ Result] The mice treated with the water suspension of O. elatus Nakai at the daily dose of 5.2, 2.6 and 1.3 g/kg showed stronger anti-hypoxia effect and loading-swimming endurance and was lower in blood lactic acid. [ Conclusion] Oplopanax elatus Nakai is endowed with effects of anti-fatigue and anti-hypoxia.