[Objective] To analyze the drug resistance of fishery-source Aeromonas hydrophila in Jiangsu Province.[Method] The epidemiological investigation was made on fishery-source A.hydrophila in Jiangsu Province during 2014-2015.A.hydrophila was detected by using API20E reagent strip.And their drug resistance was detected by using disc diffusion method.[Result] 92 positive strains of A.hydrophila were detected,the positive rate was 17.79%.The results of drug sensitivity test of 92 strains of A.hydrophila showed that the drug resistant rate of rifampin and neomycin were over 36%.The drug resistant rate of roxithromycin was more than 23%.The drug resistance rate of norfloxacin, gentamycin, enrofloxacin were lower than 10%.The drug resistant rate of kanamycin, ofloxacin, erythromycin were lower than 9%.From the hypersensibility,the hypersensibility of ofloxacin was more than 90%,the hypersensibility of kanamycin and streptomycin were more than 80%,the hypersensibility of norfloxacin, rifampicin, gentamycin and enrofloxacin were more than 70%,the hypersensibility of erythromycin was lower than 30%,and the hypersensibility of neomycin was lower than 10%.[Conclusion] In drug prevention and control of A.hydrophila in Jiangsu Province,the preferred drugs were ofloxacin, kanamycin and streptomycin.Rifampin, neomycin and roxithromycin should be avoided to use.%[目的]对江苏省渔源性嗜水气单胞菌进行耐药性分析.[方法] 2014-2015年,对江苏地区渔源性嗜水气单胞菌进行流行病学调查,用API20E试剂条检测嗜水气单胞菌,采用纸片扩散法进行耐药性分析.[结果]共检测到嗜水气单胞菌阳性菌株92份,阳性率为17.79%.对92株嗜水气单胞菌的药敏试验结果表明,在耐药率方面,利福平、新霉素的耐药率>36%,罗红霉素的耐药率>23%,诺氟沙星、庆大霉素、恩诺沙星的耐药率>10%,卡那霉素、氧氟沙星、红霉素的耐药率<9%.在高敏性方面,氧氟沙星>90%,卡那霉素、链霉素>80%,诺氟沙星、利福平、庆大霉素、恩诺沙星>70%,红霉素<30%,新霉素<10%.[结论]在江苏地区嗜水气单胞菌的药物防控中,首选药物为氧氟沙星、卡那霉素和链霉素,应尽量避免使用利福平、新霉素和罗红霉素.
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