结直肠非霍奇金淋巴瘤30例分析

摘要

目的 探讨结直肠非霍奇金淋巴瘤的临床特点、诊治及预后.方法 回顾性分析1990年1月至2009年12月收治的30例结直肠非霍奇金淋巴瘤的临床资料,应用Kaplan-Meier法、LogRank检验对其进行单因素生存预后分析.结果 肿瘤大小、有无远处转移和治疗方式是影响病人预后的主要因素(P＜0.01);性别、年龄、淋巴结有无转移及肿瘤细胞恶性程度不是影响病人预后的独立因素(P＞0.05).结论 结直肠非霍奇金淋巴瘤临床表现与结直肠癌极为相似,缺乏特异性.治疗以手术为主,术后应辅以化疗.%Objective To explore the clinical features, diagnosis, treatment and prognosis of the colorectal non-Hodgkin' s lymphoma. Methods Clinical data of 30 cases of colorectal nonHodgkin's lymphoma who were diagnosed and treated in Affiliated Hospital of Qingdao University Medical College from Jan. 1990 to Dec. 2009,were analyzed by Kaplan-Meier method and Log-Rank test. Results Tumor size,distant metastasis and the treatment were the main factors of prognosis(P ＜0. 011) ;Sex, age, lymph node metastasis and cell malignancy were not the independent prognostic factors(P＞0. 005). Conclusion The clinical presentation of colorectal non-Hodgkin's lymphoma is very similar. Surgery combined with chemotherapy may provide optimal therapy for patients with the colorectal non-Hodgkin's lymphoma.