血清胱抑素C联合尿β2微球蛋白测定对早期肾损伤评价的临床意义

摘要

Objective Serum cystatin C and urinaryβ2 microglobulin in the early detection of renal damage assessment to analyze the clinical significance.Methods 100 cases of patients Study,the 60 cases of urinary protein negative patients in group A was set,the 40 cases of patients with positive urine protein set group B,60 patients with healthy subjects as controls.For A,B groups and the control group urineβ2-microglobulin levels,and blood serum cystatin C levels were detected,the test results were compared three groups.Results By comparison,serum cystatin C levels and urinaryβ2-microglobulin levels,A,B two higher;A,B two sets of test results compared to group B than in group A.Conclusion Occurred early renal damage and in vivo serum cystatin C levels and urinaryβ2-microglobulin levels are closely related,the combined detection can improve the accuracy of diagnosis.%目的：分析血清胱抑素C联合尿β2微球蛋白检测在早期肾损伤评价中的临床意义。方法：选择100例患者进行研究，将60例尿蛋白阴性患者设为A组，将40例尿蛋白阳性患者设为B组，选择60例体检健康者为对照组。对A组、B组及对照组尿液中的β2微球蛋白含量及血液中的血清胱抑素C含量进行检测，比较三组的检测结果。结果：A组、B组血清胱抑素C含量分别为（1.66±0.28）和（4.11±0.87），尿β2微球蛋白含量分别为（0.48±0.19）和（0.82±0.22），高于对照组的（0.83±0.19）和（0.32±0.18）；且B组高于A组。结论：发生早期肾损伤和患者体内血清胱抑素C含量及尿β2微球蛋白含量密切相关，将两者联合检测能够提高诊断的准确性。