结节性筋膜炎10例临床病理分析

摘要

Objective To study the clinical and pathological features,diagnosis and differential diagnosis of nodular fasciitis.Methods A retrospective analysis of the clinical data of 10 cases of nodular fasciitis patients,combined with previous literature data of nodular fasciitis of the clinical characteristics were analyzed,HE staining,light microscopy.Results Nodular fasciitis is found mostly in young adults,made good on the forearm,clinical manifestations:mass small,rapid growth,qualitative hard or brittle,boundary is not clear.To have diagnostic significance of histological features of fibroblasts to form a"S"shaped vortex,mitoses are easy to see,no pathological karyokinesis;small fissure formation;the extravasation of red blood cells,a small amount of inflammatory cells and new capillaries abundant myxoid matrix.Conclusion The diagnosis of nodular fasciitis should grasp the clinical characteristics,diagnosis with histological features,grasp its differential diagnosis,to prevent misdiagnosis for soft tissue sarcoma.%目的：探讨结节性筋膜炎的临床病理特点、诊断及鉴别诊断。方法：回顾性分析10例结节性筋膜炎患者的临床资料，结合以往文献资料对结节性筋膜炎的临床特点进行分析，HE染色，光镜观察。结果：结节性筋膜炎多见于青壮年，好发于上肢前臂，临床表现：肿块小、生长迅速、质硬或韧、边界不清。具有诊断意义的组织学特征为纤维母细胞形成“S”形漩涡，核分裂相易见，无病理性核分裂相；小裂隙形成；红细胞外渗、有少量的炎细胞及丰富的新生毛细血管；黏液样基质。结论：诊断结节性筋膜炎应抓住其临床特点、具有诊断意义的组织学特征，掌握其鉴别诊断，防止误诊为软组织肉瘤。