日常运动对2型糖尿病患者维生素D水平的影响

摘要

objective To observe the effect of daily exercise intervention on levels of vitamin D of patients with type 2 diabetes by cross-sectional study and evaluate the possible mechanism. Method This cross-sectional study enrolled 468 patients with type 2 diabetes pa-tients and 120 apparently healthy subjects. The patients were devided into two groups based on amount of exercise per week:regular exercise group and less exercise group. Measured the plasma 25 ( OH )D levels using radioimmunoassay and mensurated the BMI of all the peo-ple. Compared the level of the index among the three groups. Results The patients with type 2 diabetes 25( OH)D levels was lower than the healthy(P<0. 01);The“regular exercise group”25(OH)D levels was higher than the“less exercise group”(P<0. 05);The 25(OH)D was negatively correlated with the BMI in patients with type 2 diabetes( P=0. 00). Conclusion The vitamin D levels of patients with T2 DM is de-creased compared with the healthy,and the daily exercise intervention can improve the vitamin D levels in patients with type 2 diabetes.%目的：通过横断面研究观察日常运动对2型糖尿病（ type 2 diabetes，T2 DM）患者VitD水平的影响并探讨其可能的机制。方法：468例T2 DM患者根据其每周运动时间量分为经常运动组和少运动组，运用放免分析法测量其血浆25（ OH）D水平，并测定BMI，同时选取120例同期健康体检者为对照，比较三组之间各指标水平。结果：T2 DM患者25（ OH）D水平较健康人低（ P＜0.01）；T2DM患者中经常运动组25（OH）D水平较少运动组高（P＜0.05）；T2DM患者25（OH）D与BMI呈负相关（P=0.00）。结论：T2 DM患者VitD水平较健康人下降，而日常运动干预可改善T2 DM患者VitD水平。