血、尿肾功能状态检查小儿过敏性紫癜患者早期肾损害中的临床意义

摘要

Objective To observe the clinical significance of blood,urine and renal function in the early stage of renal dam-age in patients with allergic purpura (HSP).Method 60 patients with HSP and who accepted treatments in our hospital,they were divided into two groups according to whether there was no kidney damage.A group without renal damage,a total of 41 cases, B group had renal damage,a total of 19 cases.Then,the blood kidney,urinary renal function status and contrast differences of the two groups were detected.Results ①Blood renal function state:The A2M、β2 mg of patients in the A group were significantly lower than those in the B group,the Trf was significantly higher than that in the B group,there was statistical significance (P <0.05);And compared with IgG between the group,there was no statistical significance (P >0.05);②urinary renal function:The mG -α1、β2 mg、MA of patients in the A group were significantly lower than those in the B group,there was statistical signifi-cance (P <0.05).Conclusion The blood,urine and kidney function as an effective indicator for early diagnosis of renal damage in HSP,which can guide the clinical treatment,so as to delay the progression of renal damage.%目的：观察过敏性紫癜（HSP）早期肾损害患者血、尿肾功能状态检查的临床意义。方法：根据有无肾脏损害将60例 HSP 患者分为两组，A 组无肾损害，共41例，B 组有肾损害，共19例，分别检测两组的血肾、尿肾功能状态并对比差异。结果：①血肾功能状态：A 组患者的 A2M、β2 mg 较 B 组显著降低，Trf 较 B 组显著升高，差异有统计学意义（P ＜0.05）；IgG 组间比较，差异无统计学意义（P ＞0.05）；②尿肾功能状态：A 组患者的 mG －α1、β2 mg、MA 均较 B 组显著降低，差异有统计学意义（P ＜0.05）。结论：血、尿肾功能状态为诊断 HSP 早期肾损害的有效指标，可指导临床治疗，从而延缓肾脏损害进展。