连续性肾脏替代治疗应用于Ⅱ型心肾综合征20例临床体会

摘要

Objective To evaluate the clinical effects of Continuous renal replacement therapy(CRRT)in type 2 cardiorenal syndrome.Method 20 type 2 cardiorenal syndrome patients who used continuous renal replacement therapy in our department were collected to measure and compare the change of mean arterial pressure(MAP),oxygenation index(PaO2 /FiO2 ),N -Termi-nal pro -B -type natriuretic peptide (NT -proBNP),serum creatinine(Cr),blood urea nitrogen(BUN)and C -reactive protein (CRP)before and after treatment.Results There were no statistical differences in MAP and CRP of continuous renal replace-ment therapy (CRRT)before and after treatment (P >0.05),but PaO2 /FiO2 ,NT -proBNP,BUN and Cr all became better(P <0.05).Conclusion The patient with type 2 cardiorenal syndrome is applied to continuous renal replacement therapy (CRRT), clinical results is satisfactory,without evident adverse reaction.%目的：探讨连续性肾脏替代治疗（CRRT）在 II 型心肾综合征中的临床疗效。方法：收集行连续性肾脏替代治疗（CRRT）的 II 型心肾综合征患者20例，分别测定并比较每例连续性肾脏替代治疗（CRRT）患者治疗前和治疗后平均动脉压（MAP）、氧合指数（PaO2／FiO2）、血浆氨基末端 B 型利钠肽前体（NT －proBNP）、血肌酐（Cr）、尿素氮（BUN）及血清 C －反应蛋白（CRP）指标的变化情况。结果：连续性肾脏替代治疗（CRRT）治疗前后 MAP、CRP 差异无统计学意义（P ＞0.05），而 PaO2／FiO2、NT －proBNP、BUN 及 Cr 均较治疗前明显好转，差异有统计学意义（P ＜0.05）。结论：连续性肾脏替代治疗（CRRT）应用于Ⅱ型心肾综合征患者，临床效果满意，无明显不良反应。