低分子肝素钙雾化吸入与氨溴索联用对小儿喘息性支气管炎血清炎性因子的影响

摘要

Objective To study the clinical effect of aerosol inhalation of low -molecular -weight heparin calcium and Am-broxol in the inflammatory factor for children with asthmatic bronchitis.Method 118 children with asthmatic bronchitis in our hospital were randomly divided into two groups,59 cases each group.The control group adopted the conventional therapy of relie-ving asthma and anti -infection therapy;on the basis,the test group aslo adopted the aerosol inhalation of low -molecular -weight heparin calcium and Ambroxol.The clinical effect and the index of CRP for two groups were compared.Results The total effective rate of test group (94.9%)was significantly higher than that of control group (79.7%)(P <0.05);the level of CRP for test group was even lower than that of controlg roup (P <0.05).Conclusion The aerosol inhalation of low -molecular -weight heparin calcium and Ambroxol has a better effect in children with asthmatic bronchitis,can enhance the clinical effective rate,reduce the level of inflammatory factor and improve the patient′s life quality as well as the physical and mental health.It shall be recommended in clinical practice.%目的：探讨低分子肝素钙雾化吸入与氨溴索联用对小儿喘息性支气管炎血清炎性因子的影响。方法：将收治的118例小儿喘息性支气管炎患者随机分为两组。对照组59例采用常规平喘、抗感染等治疗，而试验组59例在对照组基础上雾化吸入低分子肝素钙及氨溴索。比较两组患者临床疗效及血清 C 反应蛋白（CRP）的差异。结果：试验组患者临床总有效率为94.9％显著高于对照组79.7％，差异具有统计学意义（P ＜0.05）；治疗后试验组患者血清 CRP水平降低，其也显著低于同期对照组，差异具有统计学意义（P ＜0.05）。结论：低分子肝素钙雾化吸入与氨溴索联用对小儿喘息性支气管炎效果佳，其具有较高的临床有效率，降低炎性反应因子水平，进而改善其生活质量及身心健康，值得临床选择。