祛风化瘀行血通络组方联合常规西药对急性脑卒中患者神经功能及生活能力的影响

摘要

目的 探讨祛风化瘀行血通络组方联合常规西药对急性脑卒中患者神经功能及生活能力的影响.方法 选取130例急性脑卒中患者为研究对象,分成2组.对照组65例予常规西药治疗,观察组65例加用祛风化瘀行血通络组方治疗,观察治疗前后相关指标变化情况.结果 对照组显效率41.54％,总有效率81.54％,观察组显效率53.85％,总有效率95.39％,2组比较差异具有统计学意义(P＜0.05).2组治疗后HCY、TXB2、MPAR、CRP较治疗前均显著下降,治疗前后比较差异具有统计学意义(P＜0.05);观察组治疗后HCY、TXB2、MPAR、CRP较对照组治疗后下降水平更加显著,2组治疗后比较差异具有统计学意义(P＜0.05).2组治疗后NIHSS、Ashworth评分较治疗前均显著下降,ADL显著升高,治疗前后比较差异具有统计学意义(P＜0.05);而对照组颈动脉内膜中层厚度、斑块面积治疗前后比较差异无统计学意义(P>0.05),观察组治疗后较治疗前则显著下降(P＜0.05);观察组治疗后NIHSS、Ashworth评分,ADL、颈动脉内膜中层厚度、斑块面积较对照组治疗后改善水平更加显著,2组治疗后比较差异具有统计学意义(P＜0.05).结论 祛风化瘀、行血通络组方联合常规西药能改善急性脑卒中患者神经功能及生活能力.%Objective To study Effects of Qufeng Huayu Xingxue Tongluo on neurological function and life ability in patients with acute stroke. Methods 130 cases of acute cerebral apoplexy patients were divided into 2 groups, control group of 65 cases with conventional western medicine treatment, the observation group 65 cases were treated with the method of Qufeng Huayu Xingxue Tongluo, observe changes in relevant indexes before and after treatment. Results The control efficiency of 41.54％, total effective rate 81.54％, observation group efficiency 53.85％, total effective rate 95.39％, two groups were statistically significant (P＜0.05); The two groups after treatment of HCY, TXB2, MPAR, CRP on down, compared with before treatment were significantly more significant difference before and after treatment (P＜0.05), the observation group after treatment of HCY, TXB2, MPAR, CRP down level more significant compared with the control group after treatment, the two groups after treatment compared significant difference (P＜0.05); NIHSS, Ashworth score on the two groups after treatment than before treatment were significantly decreased, a significant rise in ADL, more significant difference before and after the treatment (P＜0.05), compared the carotid intima-media thickness, plaques in the area of comparative differences before and after the treatment was not significant (P＞0.05), the observation group after treatment than before treatment were significantly decreased (P ＜0.05); Observation group after treatment NIHSS, Ashworth score, ADL, carotid intima-media thickness and plaques area than the control group after treatment to improve the level is more significant, significant difference was found in comparing the two groups after treatment (P＜0.05). Conclusion The functions of blood line blood know luo formula with conventional western medicine may improve neural function in patients with acute cerebral apoplexy and life skills.