老年糖尿病患者血尿酸和抗心磷脂抗体水平变化的临床意义

摘要

Objective To investigate the changes and clinical significance of serum uric acid (UA) and anticardiolipin antibody(ACLA) in geriatric patients with diabetes mellitus(DM).Methods Serum levels of UA and ACLA and those insulin resistance were tested in DM patients with chronic complications(group A, 46 cases) and without chronic complications(group B, 30 cases) and 34 healthy examination persons (group C).Results Serum UA, fasting glucose (FPG), fasting insulin (Fins) ,HOMA-IR and ACLA were higher in groups of A and B than those in group C(P＜0.05).Conclusion Serum UA and ACLA may be taken as the markers in the diagnosis and prediction of chronic complications in geriatric patients with DM.%目的 探讨老年糖尿病患者血尿酸(UA)和抗心磷脂抗体(ACLA)水平变化的临床意义.方法 76例老年糖尿病患者分为糖尿病合并慢性并发症组(A组,46例)和糖尿病无慢性并发症组(B组,30例);健康体检人员为对照组(C组,34例).检测三组血UA,胰岛素抵抗情况和ACLA水平.结果 A组和B组血UA、空腹血糖(FPG)、空腹胰岛素(Fins)、胰岛素抵抗指数(HOMA-IR)及ACLA水平明显高于C组(P<0.05).结论 血UA和ACLA水平变化可作为糖尿病诊断及其并发症的预警指标.