168例早期胃癌淋巴结转移的病理特征分析

摘要

目的 探讨早期胃癌淋巴结转移的病理相关性因素,预测淋巴结转移的早期风险.方法 本研究选择我院收入的早期胃癌患者共168例,所有病例标本均为手术完整切除的标本,标本经病理证实癌组织均局限于黏膜以及黏膜下层,检测早期胃癌患者病理特征,结果行统计学分析.结果 本组共分析了168例早期胃癌患者标本,其中淋巴结转移28例,淋巴结转移率16.7％.早期胃癌淋巴结转移的单因素分析中显示,病灶大小、浸润深度、分化程度以及脉管侵犯为影响早期胃癌淋巴结转移的因素,结果对比差异有显著性(P＜0.05).多因素分析病灶大小、浸润深度、分化程度以及脉管侵犯为影响早期胃癌淋巴结转移的独立危险因素.结论 肿瘤病灶大小、浸润深度、分化程度以及脉管侵犯为影响早期胃癌淋巴结转移的独立危险因素,可以作为早期胃癌淋巴结转移的独立风险预测因子.%Objective To explore and discuss the pathologic correlation factors of early gastric cancer lymph node metastasis,and predict lymph node metastasis of early risk.Methods 168 cases of gastric cancer were chosen in our research,all cases were complete resection specimen from the operation specimens,specimen confirmed by pathology cancer organizations were limited to mucosa and the submucosa,detection of early stomach cancer patients pathologic characteristics,the results were studied with statistics analysis.Results Through the analysis to 168 cases with early gastric cancer,28 cases with lymph node metastasis were found,lymph node metastasis rate was 16.7％.Early stomach lymph node metastasis of single factor analysis showed,according to size,infiltration depth,lesions differentiated vascular infringement and for influence factors of lymph node metastasis early cancer of the stomach,contrasting results had statistical significant differences,P＜0.05.With multivariate factors analysis,the size,infiltration depth,lesions differentiated vascular infringed were early gastric cancer lymph node metastasis' independent risk factors.Conclusions Tumor lesion size,infiltration depth,differentiation degree and influencing vascular infringe were all early gastric cancer lymph node metastasis' independent risk factors,which can be used as independent risk predictors for early gastric cancer lymph node metastasis.