功能性电刺激改善长期卧床患者认知功能的临床对照研究

摘要

Objective The study and explore the clinical effect of functional electrical stimulation (FES) for patients with cognitive function declined due to long-term bed.Methods Sixty patients with cognitive function declined,were randomly divided into two groups:the control group and the FES treatment group.Two groups were all treated by conventional treatment way,on this basis,the FES group was treated by functional electrical stimulation extra,but not in control group.Two groups before and after treatment,the Montreal cognitive assessment (MOCA) score and auditory event related potentials P300 were tested respectively,to assess the clinical efficacy.Results There was no statistical significant difference in results of MOCA and P300 test before treatment (P ＞ 0.05).After 3 weeks,the MOCA of FES group were higher than those in the control group (P ＜ 0.05),the results of P300 test of FES group were obviously lower than those of control group,especially in P2,P3 latency and P2 amplitude (P ＜ 0.05).Conclusion The therapeutic method of FES can not only improve patients' scores of MOCA,but also decrease the results of P300 test,which can improve the cognitive function of those patients.%目的 探讨功能性电刺激(FES)改善因长期卧床导致认知功能减退的临床疗效.方法 选择60例因长期卧床导致认知功能减退的患者,随机分为FES组和对照组.两组患者均给予常规治疗,FES组加用FES治疗,对照组加用未通电流的FES治疗.两组患者治疗前后分别进行蒙特利尔认知评估量表(MOCA)评分及听觉相关电位P300检测,以评定临床疗效.结果 两组患者治疗前MOCA评分及听觉相关电位P300检测比较无统计学差异(P＞0.05);两组治疗后比较:FES组MOCA评分有明显提高(P＜0.05),听觉相关电位P300检测显示平均靶潜伏期显著缩短(P＜0.05),以P2和P3波表现突出,靶波幅显著降低(P＜0.05),以P3波较为明显.结论 FES治疗可影响因长期卧床导致认知功能减退患者的MOCA评分及P300检测结果,对其认知功能有改善作用.