酒精加双料喉风散预防化疗性静脉炎的疗效研究

摘要

Objective To evaluate the effect of alcohol plus Houfengsan on prevention of chemotherapyinduced phlebitis.Methods 116 cases of breast cancer patients were randomly divided into control group (58 cases) and test group (58 cases).In test group,a bottle of Houfengsan was mixed with 10 ml of 75％ alcohol thoroughly and applied evenly on the skin 6-10 cm upper of the puncture point,where intravenous chemotherapy was administered.This area was then covered with gauze and taped securely until 60 minutes after drug infusion completed.In control group,all patients were treated according to routine procedures.The prevalence of phlebitis in the patients from the two groups was recorded and compared.Results The incidence rate of phlebitis in test group was 8.6％ and 34.4％ in control group.The difference between the two groups was statistically significant (P ＜ 0.05).Conclusion Alcohol plus Houfengsan has anti-inflammatory,analgesic and anti-bacterial effects.Its effect on reducing prevalence rate of phlebitis induced by chemotherapy is significant.It is also safe,low-cost,easy to obtain and simple to use,which is worth being used widely,especially in primary hospitals.%目的 观察酒精加双料喉风散预防化疗性静脉炎的疗效.方法 将116例乳腺癌术后患者随机分两组,试验组58例从静脉注入化疗药开始,用双料喉风散1瓶,75％酒精10 ml调匀,均匀敷在穿刺点上方6～10 cm处,用纱布覆盖,胶布固定.直至化疗药输注完毕后60 min.对照组58例仅按常规处理.比较两组患者出现静脉炎的情况.结果 试验组的静脉炎发生率(8.6％)明显低于对照组(34.4％)(P＜0.05).结论 酒精加双料喉风散有明显的抗炎镇痛,抑菌作用功效,预防化疗药所致静脉炎疗效肯定,取材方便,安全,具有简便、经济适用的优势,值得在基层医院应用推广.