临床应用胺碘酮治疗老年冠心病并发心律失常的疗效观察

摘要

目的 探讨胺碘酮用于老年冠心病并发心律失常的临床治疗效果.方法 选取2010年6月至2015年6月本院收治的冠心病并发心律失常老年患者100例,随机分为对照组和观察组,每组50例.两组患者入院后均根据病情采取抗冠心病药物治疗,在此基础上,对照组接受慢心律片治疗,观察组采取胺碘酮治疗.1个疗程后,对两组患者的治疗效果进行评估,并以统计软件进行分析比较.结果 治疗后,两组患者24 h心绞痛发作次数及心率均较治疗前显著改善(P＜0.05),而观察组改善幅度更大,与对照组比较差异有统计学意义(P＜0.05);1个疗程后,观察组治疗总有效率为88.0％,显著高于对照组的68.0％ (P＜0.05).结论 胺碘酮可显著提高老年冠心病并发心律失常的临床疗效,且无严重用药反应,是一种安全可靠的抗心律失常药物.%Objective To investigate the clinical effect of amiodarone in the treatment of elderly patients with coronary heart disease complicating by arrhythmia.Methods 100 elderly patients with coronary heart disease complicating by arrhythmia in our hospital from June 2010 to June 2015 were randomly divided into control group and observation group,50 cases in each group.After admission,the patients of two groups were treated with anti-coronary heart disease drugs according to the disease condition.On this basis,control group was treated with Mexiletinc tablets,while observation group was treated with amiodarone.The clinical effect of two groups were observed and compared.Results After treatment,24 h heart attack frequency and heart rate of two groups significantly improved (P＜0.05),and the improvement in observation group was greater (P＜0.05).The total efficiency of observation group was significantly higher than that of control group (88.0％ vs.68.0％;P＜0.05).Conclusion Amiodarone can significantly improve the clinical efficacy of elderly patients with coronary heart disease complicating by arrhythmia,without serious drug reactions,which is a safe and reliable anti arrhythmia drug.