影响腺样囊性癌预后的多因素回归分析

摘要

Objective  A study was conducted to analyze clinical factors influencing the prognosis of adenoid cystic carcinomas. Methods  A total of 54 cases were retrospectively analyzed, and clinical factors influencing the prognosis of adenoid cystic carcinomas were selected. The data were statistically treated with Cox proportional hazard model for multivariate prognostic analysis. Results  Basaloid pathological type, terminal TNM stage, preoperative never invasion, postoperative recurrence, and distant metastasis are risk factors that affect the long-term survivalof patients, and can reduce their survival time after operation. Surgical operation plus radiotherapy/chemotherapy are protective factors for adenoid cystic carcinoma and can prolong the survival time of patients after operation. Conclusion  Pathological type, clinical stage, nerve invasion, postoperative recurrence, distant metastasis, and therapeutic methods are important factors that affect the prognosis of adenoid cystic carcinoma. Multivariate regression analysis can help determine the relationship between clinical factors and the prognosis of adenoid cystic carcinomas.%目的：分析影响腺样囊性癌预后的临床因素。方法对54例腺样囊性癌患者临床资料进行回顾性分析，筛选可能影响预后的临床因素指标，应用Cox比例风险模型进行多因素回归分析。结果病理类型为实性型，TNM临床分期为晚期，术前出现神经侵犯和术后出现复发或远处转移是影响腺样囊性癌预后的高危因素，可明显减少患者术后生存时间。综合治疗方式是保护因素，可延长患者术后生存时间。结论病理类型、临床分期、神经侵犯、术后复发、远处转移和治疗方式是影响腺样囊性癌预后的重要临床因素。应用多因素回归分析，可以确切地了解临床相关因素对疾病预后的影响。