EBV-DNA检测在儿童EBV相关非肿瘤性疾病中的应用进展

摘要

EB病毒在人群中广泛感染且与许多疾病有关.随着EBV-DNA检测技术发展,EBV-DNA检测在EB病毒相关疾病的诊断筛查、监测及治疗预后评估等方面有重要临床意义.该文对EBV-DNA检测技术的研究进展以及在儿童几种主要的EB病毒相关非肿瘤性疾病中的临床应用情况进行综述.%Epstein-Barr ( EB) virus is wildly spreaded in human and associated with many diseases. EBV-DNA load measurement by PCR has been shown to play an important role in the diagnosis of these disea-ses, a method to monitor patients and a prognosis factor of the outcome in many EBV-associated diseases. This review focuses on the development of the EBV-DNA detection technique and the advances of clinical use in sev-eral non-neoplastic EBV-associated diseases in children.