支气管肺发育不良相关性急性肾损伤的研究进展

摘要

支气管肺发育不良(bronchopulmonary dysplasia,BPD)是一种常见的新生儿呼吸系统疾病.随着医疗技术发展,早产儿的病死率降低,而早产儿出生后各种并发症发生率则逐步上升,BPD相关性急性肾损伤(acute kidney injury,AKI)便为其一.BPD相关性AKI患儿需用高浓度氧时间长,远期预后差,该文综述BPD相关性AKI的发生情况、发生机制及预防治疗的研究进展.%Bronchopulmonary dysplasia (BPD) is a common neonatal respiratory disease.The mortality rate of premature infants has reduced with the development of medical technology,while the incidence of various complications after birth,such as BPD-associated acute kidney injury (AKI),has gradually increased.Patients with BPD-associated AKI usually have poor prognosis due to exposure to hyperoxia.This review describes the occurrence,mechanism and intervention development of BPD-associated AKI.