巨细胞病毒(CMV)感染在人群中广泛流行,免疫功能异常的个体易受到感染,在新生儿和小婴儿中发病率很高。小婴儿受到CMV感染后易引起神经系统异常,因此及时诊断和治疗尤为重要。目前用于诊断CMV感染以及治疗监测中最常用的方法为荧光定量PCR法,该法敏感性和特异性较高,且操作简便不易受其他物质污染,是目前临床应用的一线方法。%Fluorescence quantitative PCR (FQ-PCR) is a more sensitive and specific method to diagnose and monitor cytomegalovirus(CMV) infection, and it is closely correlated with pp65 antigenemia levels. Measuring the CMV-DNA levels in infant urine and blood can be helpful to regulate the treatment and monitor the effects of the antivirus therapy.
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