玉屏风颗粒联合脉冲磁疗对比匹多莫德治疗小儿肺炎恢复期肺脾气虚证的疗效

摘要

Objective:To observe the clinical effect of Yupingfeng granule combined with complex pulse magnetic compare with pidotimod in spleen and lung during infantile pneumonia convalescence.Method:Eighty-two patients with the syndrome of deficiency of qi spleen and lung during infantile pneumonia convalescence were randomly divided into a treatment group (n=42) and a control group (n=40),all patients received anti-infection treatment,cough-relieving treatment,anti-asthmatic treatment and complex pulse magnetic.On the basis of this,patients in the control group were given pidotimod,and an extra treatment of Yupingfeng granule combined with complex pulse magnetic and pidotimod with in the treatment group.The efficacy and changes of lymphocyte subpopulations level were observed in two groups.Results:The disappearance time of less cough excessive phlegm,the disappearance time of pale complexion,the disappearance time of spontaneous perspiration eating less,the disappearance time of thin sloppy stool,the disappearance time of coughing,the disappearance time of expectoration,the disappearance time of crackles in lung,period of using antibiotic,the disappearance time of coughing,the disappearance time of expectoration,the disappearance time of Crackles in lung,and period of using antibiotic of the patients in the treatment group are significantly shorter than those of the patients in the control group,the differences were statistically significant (P＜0.05).The levels of IgM,IgA,IgG,CD3+,CD4+ and CD8+in the treatment group were higher than those in the control group,and the difference was significant (P＜0.05).There was no obvious adverse reaction observed in both groups.Conclusion:The clinical curative effect of Yupingfeng granule combined with complex pulse magnetic and pidotimod in the treatment of lung qi deficiency syndrome in children with pneumonia recovery is good,which is worth of application and dissemination.%目的:观察玉屏风颗粒联合复合脉冲磁疗对比匹多莫德治疗小儿肺炎恢复期肺脾气虚证的临床疗效.方法:选取肺炎恢复期肺脾气虚证患儿82例,采用数字随机法分为治疗组(n=42)与对照组(n=40),两组均给予抗生素及炎琥宁抗感染、止咳、平喘治疗,在此基础上对照组给予匹多莫德治疗,治疗组给予玉屏风颗粒联合复合脉冲磁疗,对比两组临床疗效及对免疫功能的影响.结果:治疗组在面色少华消失时间、神情倦怠消失时间、自汗少食消失时间、大便稀溏消失时间、咳嗽消失时间、咯痰消失时间、肺部哕音消失时间及抗生素使用时间方面均短于对照组(P＜0.05).治疗后,治疗组IgM,IgA,IgG,CD3+,CD4+和CD4+/CD8+水平高于对照组,CD8+水平低于对照组(P＜0.05),两组均未发生明显的不良反应.结论:玉屏风颗粒联合复合脉冲磁疗治疗小儿肺炎恢复期肺脾气虚证临床疗效良好,能够有效改善患者的临床症状,提高患儿免疫功能,值得临床推广应用.