定量动态增强MRI在头颈部肿瘤中的研究进展

摘要

The dynamic contrast-enhanced MRI (DCE-MRI) images were generated according to the signal changes aroused by the different perfusion and permeability of micro-molecule contrast agents in tissues. The common T 1WI sequences include volumetric interpolated breathhold examination (VIBE), liver acquisition with volume acceleration (LAVA), time-resolved angiography with interleaved stochastic trajectories (TWIST). The qualitative, semi-quantitative and quantitative conclusions could be drawn after the post-processing of the original DCE-MRI images. Among them, the quantitative analysis was conducted according to different parameters, and then was applied in the diagnosis, differentiate diagnosis, and the classification of tumors and tumors’ therapeutic evaluations. In this review we summarized the applications of the quantitative DCE-MRI in the head and neck neoplasms.%动态增强MRI基于小分子对比剂在灌注程度和渗透性不同的组织中分布不同而引起信号变化进行成像，常用T1WI扫描序列如快速三维容积内插屏气检查（VIBE）、肝脏快速容积采集（LAVA）序列、时间分辨随机轨道成像（TWIST）。这些序列各有优缺点。动态对比增强MR（DCE-MRI）原始图像经过后处理，可以进行定性、半定量、定量分析。定量分析根据不同的参数值，对肿瘤进行诊断、鉴别诊断，肿瘤分级及疗效评价等。就定量DCE-MRI在头颈部肿瘤中的应用进展进行综述。