腹部IVIM-DWI应用研究及进展

摘要

体素内不均一运动（IVIM）是指MR扩散加权成像（DWI）上体素内信号衰减同时包括真性水分子扩散和毛细血管网中随机血流微循环灌注，导致表观扩散系数（ADC）值反映的信息有限。采用多b值可获取系列DWI影像，根据双指数模型拟合，可同时获得组织的扩散和灌注信息，更全面地分析组织扩散成像数据。 IVIM-DWI目前已广泛应用于肝脏、胰腺、肾脏、前列腺等脏器，就该技术在腹部MR成像中的应用研究现状及进展予以综述。%Concept of intravoxel incoherent motion (IVIM) has demonstrated that the diffusion-weighted signal can be influenced not only by molecular diffusion but also by microcirculation. Therefore, apparent diffusion coefficient (ADC) values may limit the reliability in characterizing lesions. Microcirculation or perfusion effect can be distinguished from true tissue diffusion by using sufficient b value sampling and a biexponential curve fit analysis with the IVIM model.It allows a more comprehensive analysis of DWI data, and has been widely used in evaluation of liver, pancreas, kidney, prostate and other organs. This article aims to review research application and advances of IVIM-DWI in abdomen.