肌钙蛋白I定量与心肌酶谱联合检测在小儿病毒性心肌炎临床诊治中的价值

摘要

Objective To explore Troponin I quantitative and myocardial enzyme joint test in pediatric viral myocarditis clinical diagnosis in the treatment of value. Methods erum cTnI,CK ,CK-MB and LDH of 47 pediatric patients viral myocarditis(VMC) children and 53 patients with healthy controls s were tested. Results were compared and cTnI,CK,CK-MB, LDH receiver operating curves(ROC curve) were drew. Results cTnI,CK ,CK-MB, LDH results were significantly different between VMC group and control group(P<0. 01). CTnI results after 2 weeks of treatment were significantly different compared with the control group(P< 0. 01). CK,CK-MB, LDH results were not significantly different compared with the control group(P>0. 05). Conclusion cTnI quantitative and myocardial enzyme joint test in the pediatric VMC diagnosis can greatly improve the accuracy, cTnl monitoring treatment in vmc played a better role , worth to often carry out.%目的 探讨肌钙蛋白I(cTnI)定量与心肌酶谱联合检测在小儿病毒性心肌炎(VMC)临床诊治中的价值.方法 测定47例VMC患儿和53例对照组的血清cTnI、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)结果,并比较结果,绘制cTnI、CK、CK-MB、LDH受试者工作曲线(ROC曲线).结果 VMC组入院时与对照组cTnI、CK、CK-MB、LDH结果差异有统计学意义(P＜0.01);治疗2周后cTnI结果与对照组比较,差异有统计学意义(P＜0.01);CK、CK-MB、LDH结果与对照组比较,差异无统计学意义(P＞0.05).结论 cTnI定量与心肌酶谱联合检测在小儿VMC诊断中提高了准确性,cTnI在治疗效果监测中起了更好的作用,值得临床常规开展.