老年急性冠脉综合征患者血脂单项和血脂比值检测的临床价值

摘要

Objective To explore the clinical value of blood lipid levels and lipid ratios in elderly patients with acute coronary syndrome(ACS). Methods TC,TG,LDL, HDL, ApoAl, ApoB and LP(a) levels in 241 elderly patients with ACS and 181 controls were detected. TC/HDL,LDL/HDL,TG/HDL and ApoB/ApoAl ratios were calculated and analyzed. Results TG,TC/HDL and LDL/HDL in elderly ACS patients were significantly higher than those in control group. HDL and ApoAl levels were obviously lower in elderly ACS patients than those in control group. ApoAl was the independent protective factor to elderly ACS(P = 0. 012, OR = 0. 390,95%CI 0. 188 -0. 811). Conclusion Lipid ratio can be used as a predictive index,and has certain clinical value to the early prevention and diagnosis of elderly ACS.%目的 探讨血脂比值对老年急性冠脉综合征(ACS)的临床诊断价值.方法 检测241例老年急性冠脉综合征患者和181例对照者的血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、载脂蛋白(Apo)A1、ApoB和脂蛋白a[LP(a)]水平,计算TC/HDL、LDL/HDL、TG/HDL和ApoB/ApoA1比值,进行统计学分析.结果 老年ACS组TG、TC/HDL和LDL/HDL显著高于对照组;HDL和ApoA1水平显著低于对照组.ApoA1是老年ACS独立的保护因素(P=0.012,OR=0.390,95%CI为0.188~0.811).结论 血脂比值可作为老年人ACS的预测指标,对于老年ACS的早期预防和诊断具有一定的临床价值.