136例育龄妇女血清抗苗勒管激素检测分析

摘要

Objective To explore the serum anti Miillerian hormone(AMH) levels in women of childbearing age with normal menstrual cycle. Methods 136 women of childbearing age with normal menstrual cycle were selected and divided into 5 groups ac cording to their ages. Serum levels of AMH and other 6 kinds of reproductive were determinated in corpora luteum metaphase. Re-sults The comparison of serum AMH levels in different age groups had significant difference. (P = 0. 000). The serum AMH level and age showed a significant negative correlation with significant difference. (r= - 0. 385 ,P = 0. 000). There was no correlation be tween the serum levels of AMH and the other 6 kinds of hormones (P>0. 05). Conclusion AMH determination for women of childbearing age can provide reference for the evaluation of reproductive potential of infertile women and duration time of ovarian function.%目的 探讨月经正常的育龄妇女血清抗苗勒管激素(AMH)水平变化.方法 选择136例月经正常的育龄期妇女,按年龄分成5组,于黄体中期测定AMH及其他6种生殖激素.结果 21~25、26~30、31~35、36~40、41~45岁组血清AMH水平分别为5.67、4.26、4.62、1.72、0.56 ng/mL,不同年龄组血清AMH水平比较差异有统计学意义(H=25.454,P=0.000);血清AMH与年龄呈负相关,差异有统计学意义(r=-0.385,P=0.000);血清AMH与其他6项激素间均无相关关系(P>0.05).结论 测量育龄妇女血清AMH水平,为了解不孕妇女生育潜力和卵巢功能大概持续时间提供参考.