Background: Anti-müllerian hormone (AMH), a dimeric glycoprotein which is a member of the transforming growthfactor beta (TGF-b) superfamily, is produced by granulosa cells of primor-dial follicles that have undergone initial recruitment, and is thought to reflect the size and quality of the ovarian reserve. This study was to preliminarily investigate the utility of serum AMH detection during preconception care. Methods: From May 2015 to October 2016, a total of 832 women of childbearing age (24-41 years) were screened and lab-tested at the Outpatient Department of Women Health, Nanjing Women and Children Health Hospital. The population was divided into three groups and the AMH level in each group was tested. Results: The AMH levels in group A (24-30 years), group B (31-35 years), and group C (36-41 years) showed difference (P0.05). Conclusion: For women with older childbearing age, the AMH level can be introduced to detect their latent decreased ovarian reserve (DOR) and optimize their childbearing plan.
展开▼
