某地区饮食习惯和危险饮酒对男性血脂及尿酸代谢影响的研究

摘要

Objective To offer a gist to reduce the incidence of arthrolithiasis and related diseases by exploring the influence of eating habits and dangerous drinking on blood lipid and uric acid metabolism in male of this area. Methods All enrolled male sub jects were surveyed by questionnaire investigation for eating habits and drinking state. According to eating habits and drinking state,all subjects were divided into normal eating group (NDG) , abnormal eating group (ADG) and dangerous drinking group (DDG). Then,body weight,height,waistline and fasting level of triglyceride(TG) ,cholesterol(TC) ,high density lipoprotein (HDL C), low density lipoprotein(LDL C) and uric acid(UA) were measured. Results Except HDL C,levels of other indicators in ADG were significantly higher than those in NDG(P<0. 01). Levels of all indicators in DDG were significantly different with those in the other two groups (P<0. 01). The positive rates of UA in NGD,ADG and DDG were 5. 3%, 12. 5% and 20. 3%,and the positive rates of ADG and DDG were higher than that of NDG(P<0. 01). Conclusion Eating habits and dangerous drinking of this area could lead to male metabolic disturbance and promote blood uric acid level.%目的 了解东莞地区饮食习惯和危险饮酒对男性血脂和尿酸代谢的影响,为降低该地区男性成年人痛风及相关疾病的研究提供资料.方法 对所有受试人员的饮食习惯和饮酒情况采取问卷调查,根据饮食习惯和饮酒情况分为正常饮食组(NDG)、非正常饮食组(ADG)和危险饮酒组(DDG),分别测量体质量、身高、腰围,空腹检测三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低高密度脂蛋白胆固醇(LDL-C)、尿酸(UA).结果 ADG组除HDL-C外,其他各项指标的检测值均显著高于NDG组,差异有统计学意义(P＜0.01);DDG组各项指标检测值与NDG组和ADG组比较,差异均有统计学意义(P＜0.01).NDG组、ADG组、DDG组的UA阳性率分别为5.3%、12.5%、20.3%,与NDG组相比,ADG组和DDG组的UA阳性率均显著增高,差异有统计学意义(P＜0.01).结论 该地区的饮食习惯和危险饮酒可以引起男性血脂代谢紊乱,促使血UA增高.