嗜麦芽寡养单胞菌的医院感染特征及耐药性分析

摘要

目的 了解嗜麦芽寡养单胞菌的医院感染特征及耐药状况,为临床合理用药提供依据.方法 分析184株嗜麦芽寡养单胞菌的标本来源、感染科室分布及耐药状况.结果 嗜麦芽寡养单胞菌痰液检出率最高;临床分布以呼吸科病区和重症监护病区最多;耐药率较低的抗菌药物为复方磺胺、哌拉西林/他唑巴坦、左旋氧氟沙星、莫西沙星、多黏菌素;而亚胺培南、美罗培南耐药率最高;其中62株合并了其他病原菌的感染.结论 嗜麦芽寡养单胞菌具有高度和多重耐药性,临床应重视抗菌药物的合理使用,积极预防院内感染,以提高疗效和减缓多重耐药株的产生.%Objective To explore the nosocomial infection characteristics and drug resistance of Stenortrophomonas maltophilia to provide basis for rational usage of antibiotics. Methods Specimen source, Distribution of infection and drug resistance of 184 strains of Stenortrophomonas meltophilia were analyzed. Results Sputum specimen was with the highest detection rate of Stenortrophomonas maltophilia, and most clinical strains were from Department of Respiratory and Intensive Care Unit. Clinical strains of Stenotrophomonas maltophilia were relative sensitive to SXT, piperacillin/tazobactam, L-O difloxacin, moxifloxacin and polymyxin, but resistant to imipenem and meropenem. 62 clinical strains were with combined infection of other pathogenic bacteria. Conclusion Stenotrophomonas maltophilia might be with high drug-resistance and multi-drug resistance. More attention should be paid for rational usage of antibiotics and prevention of nosocomial infection to improve therapeutic effect and reduce the forming of multidrug resistance strains.