Objective To investigate the bacterial distribution and drug resistance in urinary tract infection from Sichuan Provin‐cial Antimicrobial Resistant Investigation Net during 2011-2012 .Methods The distribution and drug resistance data of pathogens isolated from urine specimens of urinary tract infection cases were collected from the members of Sichuan Provincial Antimicrobial Resistant Investigation Net ,and the results were counted and analyzed .Results There were 54 hospitals enrolling in the investiga‐tion .A total of 12 420 pathogenic strains were isolated from urinary tract infection in the survey .The top 5 predominant bacteria were Escherichia coli(46 .5% ) ,Excrement enterococcus (7 .0% ) ,K lebsiella pneumoniae (5 .8% ) ,Dung enterococcus (5 .7% ) and Pseudomonas aeruginosa(3 .7% ) .The resistant rates of Escherichia coli ,K lebsiella pneumoniae and Pseudomonas aeruginosa to imipenem were 16 .0% ,16 .7% and 16 .0% ,and to levofloxacin were 55 .2% ,28 .2% and 27 .7% ,respectively .The resistant rates of Excrement enterococcus and Dung enterococcus to vancomycin were 4 .1% and 1 .4% respectively .Conclusion Escherichiacoli and Enterococcus are still the predominant organism in urinary tract infection cases .Clinical treatment should refer to the results of drug sensitive test .%目的：了解2011～2012年四川省临床分离的尿培养病原菌的分布与耐药状况。方法收集四川省细菌耐药监测网成员单位的临床尿培养病原菌分布和药敏试验数据，进行统计及分析。结果全省54家医院参加了监测，从尿液标本中总共分离出12420株病原菌，检出率排在前5位的依次是大肠埃希菌（46．5％）、屎肠球菌（7．0％）、肺炎克雷伯菌（5．8％）、粪肠球菌（5．7％）、铜绿假单胞菌（3．7％）。大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌对亚胺培南的耐药率分别为16．0％、16．7％、15．2％；对左氧氟沙星的耐药率分别为55．2％、28．2％、27．7％。屎肠球菌和粪肠球菌对万古霉素的耐药率分别为4．1％和1．4％。结论尿路感染主要病原菌仍以大肠埃希菌和肠球菌为主，临床应根据药敏试验结果选用抗菌药物。
展开▼
