女性生殖道人乳头瘤病毒与解脲支原体感染之间的相关性研究

摘要

目的：探讨女性人乳头瘤病毒（HPV）感染情况及与解脲支原体（UU）感染之间的相关性。方法采用 PCR-反向点杂交基因分型技术对412例女性患者宫颈分泌物进行23种 HPV 亚型感染检测；将 HPV 阳性的患者设为观察组，同时随机选取50例 HPV 阴性的患者作为对照组，运用实时荧光 PCR 同时检测上述2组 UU 的感染情况。结果HPV 总的感染率为12．86％（53/412），有16种型别被检出，感染率最高的为高危 HPV 52型。HPV 阴性对照组的 UU 阳性率为30．00％（15/50），而 HPV阳性观察组中 UU 的阳性率为60．38％（32/53），明显高于 HPV 阴性对照组，差异有统计学意义（P ＜0．05）。结论HPV 感染与UU 感染具有一定的相关性，在临床治疗中应予以重视。%Objective To explore the relationship between human papilloma virus(HPV)andUreaplasma urealyticum (UU)in-fection in women.Methods A total of 412 outpatient women were checked for 23 HPV DNA types by PCR-RDB.The patients were divided into observation group with HPV infection and control group(random selection 50 cases without HPV infection).UU was detected by real-time quantitative PCR in two groups.Results The HPV positive rate was 12.86%(53/412).16 of 23 HPV types were detected.HPV52 was the most common type.The positive rates of UU for observation group(60.38%,32/53)was sig-nificantly higher than control group(30.00%,15/50),P <0.05.Conclusion The reproductive tract HPV infection in women is re-lated to UU infection.It should be paid attention to in the clinical treatment.