严重创伤患者SIRS评分与葡萄糖、乳酸、CRP水平的相关性分析

摘要

目的：探讨严重创伤患者全身炎症反应综合征（SIRS）评分与血糖、乳酸、C反应蛋白（CRP）的相关性。方法采用美国胸科医师学会（ACCP）和美国重症医学会（SCCM ）制定的SIRS诊断标准对688例严重创伤患者进行SIRS评分，检测其血葡萄糖、乳酸及CRP水平，并对它们进行相关分析。结果随着SIRS评分增加，血葡萄糖、乳酸、CRP水平也显著增高，差异有统计学意义（P＜0．05）。葡萄糖、乳酸及CRP的受试者工作特征（ROC）曲线下面积（AUC）分别为0．842、0．682、0．863。688例严重创伤患者均发生SIRS ，患者 SIRS评分与葡萄糖、乳酸、CRP具有明显的相关性（r分别为0．555、0．402、0．652，P＜0．05）。结论 SIRS评分及血葡萄糖、乳酸、CRP监测有助于提高严重创伤患者的抢救治疗成功率。%Objective To investigate the correlation of systemic inflammatory response syndrome (SIRS) score and blood glu-cose ,lactate ,C-reactive protein(CRP) in patients with severe trauma .Methods SIRS diagnostic criteria developed by American College of Chest Physicians(ACCP) and Society of Critical Care Medicine(SCCM) was adopted for SIRS scoring 688 patients with severe trauma .Their blood glucose ,lactate and CRP levels were detected ,and correlation analysis was conducted between the SIRS score and blood glucose ,lactate ,CRP levels .Results With SIRS score increasing ,blood glucose ,lactate ,CRP levels were also sig-nificantly increased ,with statistically significant difference(P<0 .05) .Areas under the receiver operator characteristic curve of glu-cose ,lactate ,and CRP were 0 .842 ,0 .682 ,0 .863 ,respectively .All 688 severe trauma patients developed SIRS .SIRS scores of pa-tients was significantly correlated with their glucose ,lactate and CRP levels(r=0 .555 ,0 .402 ,0 .652 ,P<0 .05) .Conclusion SIRS score and blood glucose ,lactate ,CRP monitoring contribute to improving the success rate of rescue therapy for patients with severe trauma .