石榴提取物对紫外线致皮肤光损伤的保护作用

摘要

紫外线照射给皮肤造成许多有害影响,包括皮肤免疫抑制、光老化等.预防及治疗紫外线照射引起的皮肤损伤,是皮肤学界关注的课题.规则摄入或外用植物抗氧化产品预防紫外线损伤已成为共识.相关研究表明,石榴提取物含有多种活性成分,如石榴多酚、黄酮类和水解单宁等,具有强大的抗氧化活性和抗炎及免疫调节作用,是一类较为理想的防治皮肤光损伤药物.%Ultraviolet irradiation has many negative effects on skin,including immunosuppression,photoaging,etc.How to effectively prevent skin damage caused by solar radiation has remained a focus in dermatology.It has been generally recognized that regular intake or external application of plant antioxidants can prevent photodamage.Pomegranate fruit extract contains many kinds of active ingredients,including pomegranate polyphenols,flavonoids,hydrolysis tannin,etc.It has been revealed that pomegranate fruit extract has antioxidant,anti-inflammatory and immunomodulatory effects,and can be exploited as an ideal agent for the prevention and treatment of skin photoaging.