旋转光栅视觉刺激生理成分的功能磁共振成像研究

摘要

目的:利用功能磁共振成像技术,观察旋转光栅刺激引起的视觉皮层生理反应,探索其反应的组成成分.方法:在1.5 T磁共振扫描仪上,对9例健康志愿者以梯度回波基础上加平面回波(GRE-EPI)成像序列法采集旋转光栅引起的视皮层反应数据,SPM99软件进行数据离线后处理.结果:旋转光栅的各种刺激成分引起不同视觉皮层中枢的兴奋.枕叶中央区域的强烈反应位于初级视觉皮层区,与白光刺激有关;两侧19区的反应与视觉运动功能有关.枕叶中央微弱反应区与形状察觉功能有关.结论:旋转光栅包含丰富的视觉信息,作为刺激源可兴奋视觉中枢的不同区域.功能磁共振成像技术可以作为研究视皮层生理的良好工具.%AIM: Using functional magnetic resonance imaging, to inspect v sual cortex physical reactions stimulated by rotating grating, and to its components. METHODS: On 1.5T MR scanner, GRE-EPI imaging sequence was carried on 9 h discover ealthy volunteers, the visual cortex response data were processed after delinearation by SPM99.RESULTS: Different components of rotating grating excited different areas of the visual cortex. Dramatic response in the central part of the occipital lobe, which was related to white light stimuli, located at primary visual cortex. Response area in bilateral Broadaman 19 areas was related to vision-motion function. And weak response area in the central part of the occipital lobe was related to shape perception.CONCLUSION: Rotating grating conclude plenty of visual information, and it excites different areas of the optic center as a stimuli. fMRI is a valuable equipment to study the physiology of visual cortex.