伊朗亚兹德地区眼眶肿瘤的病理及人群分布调查

摘要

·AIM: To review epidemiological features of 200 cases of ocular and adnexal tumors to determine the demographic and location of tumors in Yazd, Iran from 1997 to 2007.·METHODS: Retrospective, observational case series. We reviewed cases of histopathologically verified oculoorbital tumors at our institution from 1997 to 2007, and studied the distribution of patients age, pathology, origin of tumors, and tumor location in 200 consecutive cases.·RESULTS: Among the 200 cases (111 males, 89 females), 110 (55.0%) were benign tumors, 86 (43.0%) were malignant, and 4 (2.0%) were metastatic tumors. 119 tumors (59.5%) were eyelid tumors, 21 (10.5%) were orbital and 60 (30.0%) were in globe. The most frequent malignant tumors were basal cell carcinoma (BCC) (25.5%), squarnous cell carcinoma (SCC) (6.0%) and melanoma (5.5%). All types of nevus (15.0%), dermoid cyst (5.5%) and hemangioma (5.0%) were the most frequent benign tumors respectively. The age distribution of 200 patients was divided into two groups, under 18 years old and over 18 years old. In age group of less than 18 years old patients, the most common tumors were benign (90.1%) malignant and metastatic tumors were 8.4% and 1.5% respectively. While, in patients over 18 years old, the common tumors were malignant (51.1%), benign tumors were 47. 1% and metastatic tumors were 1.8%.·CONCLUSION: The pathologic profiles of orbital tumors were characterized ccording to patient's age and the location of the tumor in the globe and adnexa. The age of onset and tumor location provide us with important information for prognosis prior to biopsy or tumor re-section and to determine the treatment strategy.%目的:回顾1997/2007伊朗亚兹德地区的200例眼及附属器肿瘤的流行病学特征,确定肿瘤的人群分布及肿瘤位置.方法:回顾观察性病例报道.我们回顾1997/2007医院组织病理学确诊为眼眶肿瘤的病例,分析200例连续病例的年龄分布、病理学、肿瘤来源及肿瘤位置.结果:患者200例(男111例,女89例),其中110例(55.0%)为良性肿瘤,86例(43.0%)为恶性,4例(2.0%)为转移性肿瘤.119例(59.5%)为眼睑肿瘤,21例(10.5%)为眼眶,60例(30.0%)位于眼球.最常见的恶性肿瘤是基底细胞癌(BCC)(25.5%)、鳞状细胞癌(SCC)(6.0%)及黑素瘤(5.5%).各种类型的痣(15.0%)、度样囊肿(5.5%)、血管瘤(5.0%)是最常见的良性肿瘤.200例患者按年龄分为两组,18岁以上及18岁以下.18岁以下患者中,最常见的是良性肿瘤(90.1%),恶性肿瘤及转移性肿瘤分别占8.4%和1.5%.然而,18岁以上患者,常见的是恶性肿瘤(5 J.1%),良性肿瘤占47.1%,转移性肿瘤占1.8%.结论:眼眶肿瘤的病理学特征与患者的年龄及肿瘤在眼及附属器的位置有关.在进行活检及肿瘤切除术之前,患者的发病年龄和肿瘤位置可成为我们制定治疗方案的前提,也是预后评估的重要信息.