干燥综合征患者136例的临床特点分析

摘要

AIM:To analyze the clinical characteristics of Sj?gren's syndrome ( SS) patients with dry eye. n METHODS:The diagnostic data in 136 SS patients (272 eyes) with dry eye were retrospectively analyzed. All patients were admitted to the Department of Rheumatology and Immunology from July 2011 to June 2014 in our hospital. n RESULTS: In all 136 patients, the most commonly symptom in 88 dry eye patients was dry sensation, two or more symptoms were found in 34 patients; 232 eyes with eye lids margin were changed. The tear meniscus height of 244 eyes were <0. 3mm, with the average of 0.19±0. 11mm. The tear film break-up time ( BUT) of 206 eyes were ≤5s, 40 eyes were between 5 ~10s, 26 eyes were >10s, and with the average of 3. 5±1. 6s; The SchiemerItest ( SIt) of 200 eyes were ≤5mm/5min, 72 eyes were between 5~10mm/5min;The average score of cornea fluorescein ( CF ) staining was 5. 0± 2. 5; The average score of the meibomian gland function was 2. 7±0. 8. n CONCLUSION: In SS patients with dry eye, the symptoms such as dry sensation are usually found, meanwhile the BUTs are shorted, SIt s are reduced, CF staining are positive, tear meniscus. height are reduced, changes of eye lids margin, and the meibomian gland dysfunction, we should pay attention to the diagnosis and treatment in SS patients with dry eye.%目的：分析干燥综合征( SjÖgren's syndrome,SS)患者干眼的临床特点。n　　方法：回顾性分析2011-07/2014-06我院风湿免疫科SS患者136例272眼的干眼诊断性检查数据。n　　结果：在136例患者中：(1)干眼症状中最常见的症状是干燥感,有88例,34例有两种以上的干眼症状；(2)睑缘情况：232眼发现睑缘变化；(3)泪河高度检测：244眼<0.3mm,平均值为0.19±0.11mm；(4)泪膜破裂时间(BUT)检查：206眼BUT≤5s,40眼5s10s,平均值为3.5±1.6s；(5)SchiemerI试验(SIt)：200眼SIt≤5mm/5min,72眼5