AIM:To compare the changes of tear film stability after the combined surgery of phacoemulsification and intraocular lens ( IOL) implantation through two different clear corneal incisions (3. 0mm and 2. 2mm). METHODS: Preoperatively, 76 age - related cataract patients ( 92 eyes ) with diabetes were divided into two groups. Forty-eight eyes were enrolled in group A, they were treated with 3. 0mm clear corneal incision. And 44 eyes in group B were treated with 2. 2mm clear corneal incision. Subjective score for dryness, Schirmer I test, tear film break-up time and corneal fluorescein staining were evaluated preoperatively and 7d, 1 and 3mo postoperatively. RESULTS: Complains of dry eye and corneal fluoreascein staining was more severe in group A and tear film break-up time of group A was lower than that of group B with statistical difference ( P < 0. 05 ) at postoperative 7d and 1mo. Schirmer Ⅰ test result of group A was higher than that of group B at postoperative 1mo with statistical difference (P<0. 05). CONCLUSION: Compared with 2. 2mm group ( group B) , the symptom of dry eye was slighter and the duration was shorter than 3. 3mm group ( group A ) after phacoemulsification in cataract patients with diabetes.%目的：比较3.0mm和2.2mm两种白内障手术切口术后泪膜稳定性的变化。 方法：选取合并糖尿病的老年性白内障患者76例92眼,随机分组：A组48眼行3.0 mm透明角膜切口白内障超声乳化术；B组44眼行2.2 mm透明角膜切口白内障超声乳化术。观察术前及术后7d,1、3mo的干眼症状、基础泪液分泌、泪膜破裂时间及角膜荧光素染色情况。 结果：A组术后各时间点干眼症状明显重于 B 组,术后1wk,1mo角膜荧光染色检查明显多于B组,泪膜破裂时间明显低于B组,差异有统计学意义(P<0.05),术后1mo时,A组基础泪液分泌高于B组,两组差异有统计学意义(P<0.05)。 结论：2.2mm切口较3.0mm切口在合并糖尿病的白内障患者超声乳化术后干眼症状更轻,持续时间更短。
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