AIM:To evaluate the effect of rigid gas permeable ( RGP ) lens on the tear film and the visual quality in adolescents with a double-pass system. METHODS:This was a prospective study comprised 23 myopia patients ( 39 eyes ) wearing rigid gas permeable contact lens ( RGP ) between Jun. 2015 and Aug. 2015 in the Department of Ophthalmology of Jinling Hospital. Uncorrected visual acuity ( UCVA ) , sphere refractive, cylinder refractive, Schirmer I test, tear film break-up time ( BUT ) , the visual quality and the tear film quality with OQAS II were obtained before and 1wk, 1, 3, 6mo after wearing. The data was analyzed using t-test and One-way. RESULTS:The UCVA in before and after 1wk, 1, 3, 6mo were 0. 23±0. 10, 0. 81±0. 23, 0. 99±0. 11, 1. 01±0. 09, 0. 95±0. 14, the difference was statistically significant ( F=723. 36, P0. 05). Schirmer I test showed no statistically significant difference before and after wearing RGP ( F=4.88, P>0. 05). The stability of tear film was reduced after wearing RGP, and the difference was statistically significant (F=135. 11, P0.05)。戴镜前及戴镜后1wk,1、3、6mo 时的Schirmer I试验结果分别为19.05±3.67、19.13±4.60、17.60±3.39、17.51±2.86、17.56±4.40mm,组间比较差异无统计学意义(F=4.88,P>0.05)；戴镜前及戴镜后1wk, ；1、3、6 mo时的BUT试验结果分别为11.15±1.81、8.90±1.93、8.31±1.84、7.00±1.78、5.95±1.49s,组间比较差异有统计学意义(F=135.11,P<0.01)。戴镜前及戴镜后1wk,1、3、6mo时的MTF cut off分别为40.89±7.04、33.47±8.61、33.48±7.38、33.08±8.88、33.24±10.31c/deg,OSI值分别为0.40±0.15、0.76±0.38、0.76±0.32、0.86±0.32、0.83±0.51,客观泪膜质量分别为0.80±0.23、1.25±0.51、1.28±0.47、1.29±0.53、1.40±0.65,差异有统计学差意义(F=6.16、19.23、10.62,P<0.01)。 结论：角膜塑形镜可快速降低球镜度数,提高UCVA,对泪液基础分泌无影响,但可以缩短泪膜破裂时间,降低泪膜的稳定性,影响视觉质量。
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